WebMultidrug resistance-associated protein 1 ( MRP1) is a protein that in humans is encoded by the ABCC1 gene. [5] [6] Function [ edit] The protein encoded by this gene is a member of the superfamily of ATP-binding … Web9 aug. 2024 · MDR is typically associated with transmembrane proteins mediating efflux of administered drugs, thereby keeping their intracellular concentration below the threshold required to kill cells. Although expression assays based on flow cytometry and immunostaining have shown that multidrug resistance-associated protein 1 (MRP1) is …
Multidrug resistance-associated protein 1 expression is under the ...
WebProtein multidrug resistance-associated protein 5-like isoform X1 Gene LOC106612343 Status UniProtKB unreviewed (TrEMBL) Organism Salmo salar (Atlantic salmon) Amino acids 1417 Protein existence Predicted Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback … WebAcum 2 zile · Antibiotic resistance (AR) is posing a serious threat to the global health. By accumulating intrinsic resistant mutations or horizontally transferred AR genes, bacteria can evolve to be... famous cal poly grads
Expression and function of multidrug resistance protein 1 and …
WebThe multidrug resistance 1 (MDR1) gene, encoding the membrane-resident P-glycoprotein (P-gp) that belongs to a family of ATP-binding cassette (ABC) transporters, has been found to be a HIF-1α target gene. 11 The multidrug resistance associated protein 1 (MRP1), another ABC transporter encoded by the ABCC1/MRP1 gene, is a 190 kDa … Web16 aug. 2000 · In 1992, Cole et al. (5) discovered a second type of drug pump in MDR cancer cells, the multidrug resistance-associated protein (MRP). While the human genome encodes only two P-gp's (6) [and a distant relative of P-gp, the bile salt transporter (7) ], it is shown to contain many more genes related to MRP (8,9). Web1 mai 2005 · ABC proteins that confer drug resistance include (but are not limited to) P-glycoprotein (gene symbol ABCB1), the multidrug resistance protein 1 (MRP1, gene … famous calvinist pastors today