WebConcomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of having taken an MAOI [see Warnings and Precautions (5.6), Drug Interactions (7)] • Known or suspected gastrointestinal obstruction, including paralytic ileus [see Warnings and Precautions (5.12)] • Hypersensitivity to meperidine (e.g., anaphylaxis) [see Adverse ... WebMEPERGAN (meperidine HCl and promethazine HC l) injection, for intramuscular or intravenous use, CII . Initial U.S. Approval: 1961 . ... (MAO) i nhibitors can result in coma, severe respiratory depression, cyanosis and hypotension. Use of MEPERGAN Injection with MAO inhibitors is contraindicated. (4, 7)
Anesthetic Considerations for Patients on Antidepressant Therapy …
WebMaprotiline side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Report … WebIrreversible MAOIs should be discontinued 2 weeks before surgery or switched to a reversible MAOI (moclobemide), which needs to be stopped only 24 hours before surgery. 52 Because dopamine is a substrate for MAO, it should be administered at much lower doses in patients taking an MAOI or TCA. Use of meperidine with an MAOI can lead to ... barber berlin neuruppin
Monoamine oxidase inhibitors (MAOIs) - Mayo Clinic
WebNumerous cases of Meperidine toxicity with MAO inhibitors have been reported. [3, 8, 12-17] The typical presentation in these cases is that patients experience severe hypertension … Web3A4 (CYP3A4) inhibitors may result in an increase in meperidine plasma concentrations, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression. In addition, discontinuation of a concomitantly used cytochrome P450 3A4 CYP3A4) inducer may result in an increase in meperidine plasma … WebFurther, we show that morphine-, meperidine- and tramadol-induced analgesia is markedly decreased in SERT-/- mice. These studies suggest that caution seems warranted in prescribing or not warning patients receiving SSRIs or MAOIs that dangerous side-effects may occur during concurrent use of tramadol and similar agents. barber berlin pankow