WebSep 9, 2015 · Autophagy inhibition by DC activation leads to the aggregation of endogenous antigens in DALISs and down-regulation of MHC II presentation. (A) Immunofluorescence confocal microscopy (ICM) analysis for NBR1 and p62 was performed on LPS-stimulated DCs (left). ... The FYVE-less mutant did not localize to … WebMar 1, 2024 · Autophagy process mainly refers to the formation and degradation of the membrane, and the source of autophagy membrane is still controversial, most of them are bilayer membrane, sometimes multilayer or monolayer, the theory of endoplasmic reticulum source is widely recognized [14].When the autophagosome membrane appears, …
FYCO1 FYVE and coiled-coil domain autophagy adaptor 1
WebSep 20, 2016 · The Autophagy linked FYVE domain protein (Alfy) [gene name, WD40 repeat and FYVE domain protein 3 (Wdfy3)] is a member of the Beige and Chediak-Higashi (BEACH) domain containing proteins, a family of proteins implicated in vesicle trafficking and membrane dynamics (Isakson et al., 2013; Simonsen et al., 2004).As its name implies, … WebPIKfyve inhibitors cause cell death also in A-375 melanoma cells, which depend on autophagy for growth and proliferation, due to impaired lysosome ... Single copy genes, encoding similarly-structured FYVE-domain–containing phosphoinositide kinases exist in most genomes from yeast to man. The plant A. thaliana has several copies of ... teltonika rut955 datasheet
Immobility-associated thromboprotection is conserved across …
WebRecently, the autophagy-related protein, double FYVE domain-containing protein 1 (DFCP1/ZFYVE1) was shown to reside at the interface of the endoplasmic reticulum and … WebThe variation in autophagy markers can be detected by fluorescence, Western blotting, flow cytometry, and multifunctional microplate reader. Among these studies, exogenous GFP-LC3 protein was the ... WebJul 15, 2024 · Autophagy biomarkers play an important role as an indicator of autophagy during normal physiological processes, pathogenic processes or pharmacological responses to drugs. ... domains, which are placed in tandem on the C-terminus, it also contains a zinc finger domain on the N-terminus. FYVE domains have the capacity to bind to … teltonika rut240 admin